Clinically, dosage is titrated to provide adequate analgesia and may be limited by adverse reactions, including respiratory and CNS depression. Opioid antagonists, such as naloxone, are specific antidotes to respiratory depression resulting from opioid overdose. For clinically significant respiratory or circulatory depression secondary to oxycodone overdose, administer an opioid antagonist. Pregnant rabbits were treated with 1, 5, 25, and 125 mg/kg oxycodone hydrochloride (0.3, 2, 8, and 40 times the human daily dose of 60 mg/day, respectively, based on a mg/m2 basis) during the period of organogenesis. Oxycodone did not cause adverse effects to the fetus at exposures up to 40 times the human dose of 60 mg/day. The 25 mg/kg and 125 mg/kg doses high doses produced maternal toxicity characterized by decreased food consumption and body weight gain.
Patient Counseling Information
Over time, your brain might lean on the drug just to feel okay, leading to opioid addiction or what doctors call opioid use disorder. OxyContin is a type of medication that falls into the category of opioids. People commonly use them to help treat pain, but doctors do not recommend them for long-term use.
What Types of Treatment Are Available for Oxycontin Addiction?
Patients start on a moderate and safe dose of the treatment drug, which is then slowly reduced Sobriety over time. Generally, recovery is attained and held the longest when treatment is ongoing for at least one year. When people take OxyContin in high doses, they can experience a high marked by euphoria or a sense of overall well-being. For this high to take effect, a person would have to circumvent the time-release function by either chewing and swallowing, crushing and injecting or crushing and snorting the drug. Another main difference between opiates and opioids is their legality.

1 Controlled Substance
- The tablets are meant to be swallowed whole, so the active ingredient can be slowly released over time.
- If you are taking the oxycodone extended-release tablets, swallow them whole; do not chew, break, divide, crush, or dissolve them.as you may receive too much oxycodone at once instead of slowly over 12 hours.
- The oxycodone in OXYCONTIN may cause spasm of the sphincter of Oddi.
- With OxyContin addiction, a person often experiences strong and uncontrollable drug cravings.
MAT is likely to be a central component of most people in recovery from OxyContin addiction. Methadone or Suboxone may be effective for alleviating the intensity of withdrawal symptoms during OxyContin detox. Methadone may also be beneficial throughout ongoing treatment for opioid addiction.
Immersion Recovery Center offers free no-obligation insurance benefits checks. However, you can call Guardian Recovery, the parent company for Immersion Recovery, to find out about our locations in NJ, ME & CO that accept Medicaid and Medicare from those states. We work with most major insurance How Addictive Is OxyContin companies and we’re are here to help you with this process.

Misusing Oxycontin makes these risks and side effects way worse. The risk is even higher if you’ve never used opioids before or you take more than your body can handle. Overdose can happen in minutes, sometimes without any warning at all. Taking too much Oxycontin or using it the wrong way—like crushing, snorting, or injecting—boosts your risk of overdose.
OxyContin Withdrawal Symptoms

Opioid use and addiction have reached epidemic levels in the United States. OxyContin is a controlled-release version of oxycodone designed to provide extended pain relief over 12 hours. In contrast, regular oxycodone is an immediate-release medication that delivers effects more quickly but requires more frequent dosing. Overdose occurs when excessive amounts of the drug overwhelm the central nervous system, causing life-threatening symptoms such as severe respiratory depression, unconsciousness, and cardiac arrest.
